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CXCL9/MIG ELISA Kit & CXCL10 ELISA Kit
A Biomarker for cancer, ARDS and heart failure

Alternative name:

  • Monokine induced by interferon-gamma (MIG)
  • C-X-C motif chemokine 9 (CXCL9)
  • Small-inducible cytokine B9

T-cell-mediated immune responses play important roles in the progression of atherosclerotic disease. Studies have linked various inflammatory biomarkers with the burden of coronary artery calcification, but the significance of T-cell-specific chemokines in coronary artery calcification has not been confirmed. We aimed to examine the association between serum levels of the monokine induced by gamma interferon (MIG) and the coronary artery calcium score (CACS).
METHODS: We enrolled 456 individuals (285 men, 66.5±5.8 years) who were registered in the Mapo-gu public health center cohort. We selected 228 individuals with a CACS of more than 100 and 228 age-matched and sex-matched individuals with a CACS of less than 100. All participants underwent coronary computed tomography for CACS measuring. Clinical and laboratory variables including serum MIG levels were analyzed at the time of enrollment.
RESULTS: The serum level of MIG was significantly higher in participants with a CACS of more than 100 (152.1±119.1 vs. 130.3±112.9, P=0.046). Serum MIG levels correlated significantly with CACS (r=0.113, P=0.016), and higher levels of MIG were associated with severe plaque burden (CACS>400, P=0.025). Multiple linear regression analysis showed that serum MIG levels were associated independently with CACS after controlling for confounding factors and medications (β=0.114, P=0.026).
CONCLUSION:Serum MIG levels were associated independently with CACS after adjusting for traditional cardiovascular risk factors. These findings suggest that MIG may be used as a novel biomarker for T-cell inflammation and atherosclerotic plaque burden in humans.

Yu HT et al. Coron Artery Dis. 2015 Mar 9
Ultrasensitive CXCL9/MIG (Human) ELISA Kit
Code No.: SK00435-02
Size: 96T
Price: $390.00 USD
Standard range:4.7-300 pg/ml
Sensitivity:1 pg/ml
Sample Type: serum, plasma
Intra-CV:4-6%
Inter-CV: 8-12%
Data Sheet: PDF
human CXCL9 ELISA Kit SK00435-01 from aviscera bioscience CXCL9 (Human) ELISA Kit
Code No.: SK00435-01
Size: 96T
Price: $360.00 USD
Standard range:62-4000 pg/ml
Sensitivity:20 pg/ml
Sample Type: serum, plasma
Intra-CV:4-6%
Inter-CV: 8-12%
Data Sheet: PDF
human CXCL10 ELISA Kit from aviscera bioscience CXCL10 (Human) ELISA Kit
Code No.: SK00436-01
Size: 96T
Price: $360.00 USD
Standard range:31-2000 pg/ml
Sensitivity:20 pg/ml
Sample Type: serum, plasma
Dilution Factor: 1000-2000 for serum
Intra-CV:4-6%
Inter-CV: 8-12%
Data Sheet: PDF
Human CXCL7 ELISA Kit from aviscera bioscience NAP-2/CTAP III/CXCL7 (Human) ELISA Kit
Code No.: SK00434-01
Size: 96T
Price: $360.00 USD
Standard range:31.2-2000 pg/ml
Sensitivity:15 pg/ml
Sample Type: serum, plasma
Dilution Factor: 1000-2000 for serum
Intra-CV:4-6%
Inter-CV: 8-12%
Data Sheet: PDF

 

Name
Code No.
Size
Price ($)
CXCL9 (Human) Ultrasensitive ELISA Kit SK00435-02 96 T 390.00
CXCL9 (Human) ELISA Kit SK00435-01 96 T 360.00
CXCL10 (Human) ELISA Kit SK00436-01 96 T 360.00
CXCL7 (Human) ELISA Kit SK00434-01 96 T 360.00