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Endothelial Lipase (EL)/LIPG ELISA, Antibody, Protein

Alternative name:

  • LIPG
Ishida T et al. J Clin Invest.2003 Feb;111(3):347-55.
Expression of Endothelial Correlates with the Size of Neointima in a Murine Model of Vascular Remodeling
im:Endothelial lipase (EL) regulates plasma high-density lipoprotein-cholesterol (HDL-C) levels by promoting HDL catabolism. However, it remains unknown whether the inhibition of EL has beneficial effects on the genesis of vascular diseases. Here, we investigated the role of EL on vascular remodeling in mice.Methods: Vascular remodeling was developed by ligation of the left common carotid artery and neointimal lesions were histologically compared between EL-knockout (ELKO), EL-transgenic (ELTg), and wild-type (WT) mice. HDL was isolated from these mice, and effects of the HDL on cell growth and Erk activation were evaluated in vitro using cultured vascular smooth muscle cells.Results: Plasma HDL-C levels were 62% higher in ELKO and 13% lower in ELTg than in WT mice, after the carotid ligation. The size of neointimal lesion was significantly larger in ELTg and smaller in ELKO than in WT mice. Vascular expression of adhesion molecules was lower in ELKO and higher in ELTg compared with WT mice. Moreover, oxidative stress was attenuated in ELKO mice. HDL isolated from ELKO, ELTg, and WT mice inhibited expression of intercellular adhesion molecule-1, angiotensin II-induced activation of Erk, and growth of cultured vascular smooth muscle cells, whereas EL expression itself did not affect cell migration or growth.Conclusion: EL expression modulates vascular remodeling as well as plasma HDL-C levels. EL inactivation may increase HDL particles that can inhibit smooth muscle cell growth and migration.
Sun L, et al. J Atheroscler Thromb.2012 Sep 10. [Epub ahead of print]
   
Human Endothelial Lipase (EL) ELISA Kit
Code No.: SK00276-08
Size: 96 T
Price: $460.00 USD
Standard range:15.6-1000 ng/ml
Sensitivity: 800 pg/ml
Sample Type: serum, plasma, cell cultures
Sample require: 200 ul for serum or plasma
Intra-CV: 4-8%
Inter-CV: 8-10%
Data Sheet: PDF

mouse rat endothelial lipase elisa kit sk00276-02 from aviscera bioscience

Mouse/Rat Endothelial Lipase (EL) ELISA Kit
Code No.: SK00276-02
Size: 96 T
Price: $460.00 USD
Standard range:3.2-2000 ng/ml
Sensitivity: 2.5 ng/ml
Sample Type: serum, plasma, cell cultures
Sample require: 50 ul for serum or plasma
Intra-CV: 4-8%
Inter-CV: 8-10%
Data Sheet: PDF
   
Human Endothelial Lipase Recombinant
Code No.: 00276-01-100
Size: 100 ug
Price: $360.00 USD
Protein ID:Q9Y5X9
Gene ID: 9388
MW: 55.3 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 95%
Data Sheet: PDF
Human Endothelial Lipase Recombinant
Code No.: 00276-02-10
Size: 10 ug
Price: $350.00 USD
Protein ID:Q9Y5X9
Gene ID:9388
MW:72 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 95%
Data Sheet: PDF
Anti Human EL IgG
Code No.: A00276-01-100
Size: 100 ug
Price: $220.00 USD
Host: Rabbit
Antigen: human EL Rec.
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC
Working Dilution: 1-2 ug/ml)
Data Sheet: PDF
Anti Human EL IgG
Code No.: A00276-01-100
Size: 100 ug
Price: $220.00 USD
Host: Rabbit
Antigen: human EL Rec.
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC
Working Dilution: 1-2 ug/ml)
Data Sheet: PDF
Anti Human EL IgG
Code No.: A00276-01-100
Size: 100 ug
Price: $220.00 USD
Host: Rabbit
Antigen: human EL Rec.
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC
Working Dilution: 1-2 ug/ml)
Data Sheet: PDF
Anti Human EL IgG
Code No.: A00276-01-100
Size: 100 ug
Price: $220.00 USD
Host: Rabbit
Antigen: human EL Rec.
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC
Working Dilution: 1-2 ug/ml)
Data Sheet: PDF
 

 

Name
Code No.
Size
Price ($)
Endothelial Lipase (Human) ELISA Kit SK00276-08 96 T 460.00
Endothelial Lipase (Human) ELISA Kit SK00276-01 96 T 420.00
Endothelial Lipase (Rat/Mouse) ELISA Kit SK00276-02 96 T 420.00
Endothelial Lipase (Human) ELISA Kit SK00276-06 96 T 460.00
Endothelial Lipase (Human) , Rec.
100 ug
360.00
Endothelial Lipase (Human) , Rec.
100 ug
360.00
Anti EL (Human) , rabbit IgG , biotinylated
A00276-01-50B
50 ug
360.00
AntiEndothelial Lipase (Human) , rabbit IgG
100 ug
220.00