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GDF-11/Bone Morphogenetic Protein 11 (BMP11) Recombinant, Antibody, ELISA Kit
 
 
 
 
Parabiosis experiments indicate that impaired regeneration in aged mice is reversible by exposure to a young circulation, suggesting that young blood contains humoral "rejuvenating" factors that can restore regenerative function. Here, we demonstrate that the circulating protein growth differentiation factor 11 (GDF11) is a rejuvenating factor for skeletal muscle. Supplementation of systemic GDF11 levels, which normally decline with age, by heterochronic parabiosis or systemic delivery of recombinant protein, reversed functional impairments and restored genomic integrity in aged muscle stem cells (satellite cells). Increased GDF11 levels in aged mice also improved muscle structural and functional features and increased strength and endurance exercise capacity. These data indicate that GDF11 systemically regulates muscle aging and may be therapeutically useful for reversing age-related skeletal muscle and stem cell dysfunction.
Loffredo FS et al. Cell. 2013 May 9;153(4):828-39
human GDF11 is a growth factor

 

Human/Mouse/Rat BMP11/GDF-11 Recombinant
Code No.: 00337-06-100
Size: 100 ug
Price: $420.00 USD
Protein ID:NP_034402
Gene ID: NM_010272
MW: 15 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 95%
Data Sheet: PDF
western blot analysis of mouse serum samples by rabbit anti human mouse GDF-11 antibody from aviscera bioecience
Anti Human/Mouse/Rat BMP11/GDF-11 IgG
Code No.: A00337-06-100
Size: 100 ug
Price: $220.00 USD
Host:Rabbit
Immunogen: h/m/r GDF-11, mature
Antibody Type: Polyclonal IgG
Purification: Protein A
Application: E, IHC, WB
Data Sheet: PDF
Anti Human/Mouse/Rat BMP11/GDF-11 IgG
Code No.: A00337-06-100
Size: 100 ug
Price: $220.00 USD
Host:Rabbit
Immunogen: h/m/r GDF-11, mature
Antibody Type: Polyclonal IgG
Purification: Protein A
Application: E, IHC, WB
Data Sheet: PDF
Name
Code No.
Size
Price ($)
       
GDF-11/BMP11 (Human Mouse Rat), Rec.
50 ug
260.00
GDF-11/BMP11 (Human Mouse Rat), Rec.
100 ug
420.00
GDF-11/BMP11 (Human Mouse Rat), Rec.
1mg
3800.00
GDF-11/BMP11 (Human Mouse Rat), Biotinylated
50 ug
260.00
Anti GDF-11/BMP11 (Human Mouse Rat) IgG
100 ug
290.00
Anti GDF-11/BMP11 (Human Mouse Rat) IgG Biotinylated
50 ug
350.00