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IL-33 ELISA Kit, Antibody & Proteins
A Biomarker for Cardiovascular Diseases

Alternative name:

  • IL-1F11

 

Dysfunction of the innate immune system is involved in the pathogenesis of Alzheimer’s disease (AD); however, the pathophysiological mechanisms underlying these dysfunctions are unclear. Here we report that stimulation of IL-33/ST2 signaling rescues memory deficits and reduces the accumulation of ß-amyloid in APP/PS1 mice that exhibit select pathologies associated with AD. Although impaired IL-33/ST2 signaling is associated with early progression of AD, IL-33 injection rescues contextual memory deficits and reduces the accumulation of ß-amyloid in APP/PS1 mice. IL-33 skews the microglia toward an alternative activation state with enhanced Aß phagocytic capacity and elevated antiinflammatory gene expression, which results in a decreased proinflammatory response in the brain. Thus, this study suggests that IL-33 can be developed as a new therapeutic intervention for AD.
Interleukin-33 is a newly recognized cytokine of the IL-1 family. Unlike its other members IL-1α, IL-1β and IL-18, interleukin-33 induces predominantly Th2-skewed immune responses. In this context, the effects of IL-33 are mostly anti-inflammatory. However, depending on the actual cytokine and cellular milieu, IL-33 can promote both Th1 and Th2 immune reactions. Most importantly for cardiology and cardiac surgery, IL-33 has emerged to represent the as yet unknown ligand of the orphan receptor ST2. Before the advent of IL-33, the ST2 receptor, currently recognized as the soluble one of its two isoforms, was considered to be an unfavorable prognostic marker in myocardial infarction, congestive heart failure and trauma/sepsis shock patients. Now we know that IL-33, when bound to the cellular membrane-anchored ST2L isoform of the receptor, can have certain beneficial effects on the aforementioned conditions. Various forms of IL-33 interaction with the respective isoforms of its cognate receptor are discussed here. The focus is on physiological and prognostic values in cardiac patients.
Kunes P, et al. Thorac Cardiovasc Surg. 2010 Dec;58(8):443-9. Epub 2010 Nov 26.
human IL-33
 
new human IL-33 elisa kit for serum samples assay
Human IL-33 ELISA Kit
Code No.: SK00277-06
Size: 96T
Price: $420.00 USD
Standard Range:78-5000 pg/mL
Sensitivity:15 pg/mL
Sample Type: serum,cell cultures,
Sample volume: 100 uL
Dilution factor: N/A
IntraCV: 4-6%
InterCV: 8-12%
Protocol:PDF
new human IL_33 elisa kit for human serum assay
Human IL-33 ELISA Kit
Code No.: SK00277-09
Size: 96T
Price: $420.00 USD
Standard Range:78-5000 pg/mL
Sensitivity:15 pg/mL
Sample Type: serum,cell cultures,
Sample volume: 100 uL
Dilution factor: N/A
IntraCV: 4-6%
InterCV: 8-12%
Protocol:PDF
mouse IL-3 elisa kit from aviscera bioscience
Mouse IL-33 ELISA Kit
Code No.: SK00277-03
Size: 96T
Price: $390.00 USD
Standard Range:25-1500 pg/mL
Sensitivity:10 pg/mL
Sample Type: serum,cell cultures,
Sample volume: 100 uL
Dilution factor: N/A
IntraCV: 4-6%
InterCV: 8-12%
Protocol:PDF
Human IL-33 Recombinant
Code No.: 00277-01-100
Size: 100 ug
Price: $460.00 USD
Protein ID:O95760
Gene ID: 90865
MW: 18 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 95%
Data Sheet: PDF
  Anti IL-33 (Human) IgG
Code No.: A00277-01-100
Size: 100 ug
Price: $260.00 USD
Target Protein ID:O95760
Target Gene ID: 90865
Host: Rabbit
Immunogen: Human IL-33 Rec.
Antibody Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC (2-4 ug/ml)
Data Sheet: PDF
  Anti IL-33 (Human) Monoclonal Antibody
Code No.: A00277-02-100
Size: 100 ug
Price: $360.00 USD
Clone: 2E2E2G6
Target Protein ID:O95760
Target Gene ID: 90865
Host: Rabbit
Immunogen: Human IL-33 Rec.
Antibody Type: Monoclonal
Purification: Protein G
Applications: ELISA (capture)
Data Sheet: PDF
 

 

 

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Name
Code No.
Size
Price ($)
Human IL-33 ELISA Kit (Serum)
96 T
420.00
Human IL-33 ELISA Kit (Serum) SK00277-06B 192 T 800.00
Human IL-33 ELISA Kit (Serum) SK00277-06F 480 T 1800.00
Human IL-33 ELISA Kit (Serum) SK00277-06T 960 T 3000.00
Human IL-33 ELISA Kit (Serum)
96 T
420.00
Human IL-33 ELISA Kit (Serum) SK00277-09B 192 T 800.00
Human IL-33 ELISA Kit (Serum) SK00277-09F 480 T 1800.00
Human IL-33 ELISA Kit (Serum) SK00277-09T 960 T 3000.00
Mouse IL-33 ELISA Kit SK00277-03 96 T 390.00
Human Soluble IL-1R4/ST2 ELISA Kit
96 T
390.00
Mouse Soluble IL-1R4/ST2 ELISA Kit
96 T
390.00
IL-33 (Human) recombinant 00277-01-100 100 ug 460.00
IL-33 (Human) Recombinant 00277-01-50 50 ug 310.00
Anti IL-33 (Human) IgG A00277-01-100 100 ug 260.00
Anti IL-33 (Human) IgG Biotinylated A00277-01-50B 50 ug 300.00
Anti IL-33 (Human) Monoclonal Antibody A00277-02-100 100 ug 320.00
Anti IL-33 (Human) Monoclonal Antibody A00277-02-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-03-100 100 ug 320.00
Anti IL-33 (Human) Monoclonal Antibody A00277-03-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-04-100 100 ug 260.00
Anti IL-33 (Human) Monoclonal Antibody A00277-04-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-10-100 100 ug 220.00
Anti IL-33 (Human) Monoclonal Antibody A00277-10-1000 1000 ug Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-10-50B 50 ug 320.00
Anti IL-33 (Human) Monoclonal Antibody A00277-10-500B 500 ug Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-11-100 100 ug 220.00
Anti IL-33 (Human) Monoclonal Antibody A00277-11-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-11-50B 50 ug 320.00
Anti IL-33 (Human) Monoclonal Antibody A00277-12-100 100 ug 220.00
Anti IL-33 (Human) Monoclonal Antibody A00277-12-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-12-50B 50 ug 320.00
Anti IL-33 (Human) Monoclonal Antibody A00277-14-100 100 ug 220.00
Anti IL-33 (Human) Monoclonal Antibody A00277-14-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-14-50B 50 ug 320.00
Anti IL-33 (Human) Monoclonal Antibody A00277-15-100 100 ug 220.00
Anti IL-33 (Human) Monoclonal Antibody A00277-15-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-15-50B 50 ug 320.00
Anti IL-33 (Human) Monoclonal Antibody A00277-16-100 100 ug 220.00
Anti IL-33 (Human) Monoclonal Antibody A00277-16-1000 1 mg Inquire
Anti IL-33 (Human) Monoclonal Antibody A00277-16-50B 50 ug 320.00
IL-33 (Mouse) Rec. 00277-03-05 5 ug 149.00