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Soluble Triggering receptor expressed on myeloid cells 1 (TREM1) ELISA Kits
Soluble Triggering receptor expressed on myeloid cells 2 (TREM2) ELISA Kit
Soluble TREM-1 is a New Biomarker for Infection, Sepsis and Pneumonia

Alternative name:

  • Triggering receptor expressed on monocytes 1
  • CD_antigen=CD354
The plasma level of soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) has been shown to be helpful in identifying critically ill patients with infection. However, it remains unknown whether it can be used to predict prognosis in patients with severe sepsis. This study investigated whether various inflammatory mediators, including sTREM-1, could be used as reliable markers to predict the prognosis of patients receiving early goal-directed therapy (EGDT). We prospectively enrolled patients 18 years or older with severe sepsis from April 2009 to May 2010 at a 2,000-bed university hospital. Patients were eligible if the initial resuscitation according to EGDT protocol was immediately performed at the emergency department. Plasma sTREM-1, C-reactive protein, and procalcitonin concentrations were measured on days 0, 3, 7, and 14. Soluble TREM-1 concentrations were significantly higher at admission and pre-EGDT in nonsurvivors (n = 16) than in survivors (n = 47) (514.1 pg/mL [interquartile range, 412.7-1,749.5 pg/mL] vs. 182.4 pg/mL [interquartile range, 54.3-327.0 pg/mL]; P = 0.001). Procalcitonin and C-reactive protein levels did not significantly differ, whereas central venous oxygen saturation and lactate levels at admission were significantly different between the two groups. The only sTREM-1 level remained significantly higher in nonsurvivors until death. On multivariate regression analysis, log(sTREM-1) (P = 0.028), central venous oxygen saturation (P = 0.022), and Simplified Acute Physiology Score II (P = 0.048) values at admission were independently significant. These results suggest that plasma sTREM-1 level at admission could be used as a marker to identify patients with a poor prognosis despite complete initial resuscitation in severe sepsis.
Jeong SJ, et al., Shock. 2012 Jun;37(6):574-8.
Siranović M,  , et al. Acta Clin Croat. 2011 Sep;50(3):345-9.

PURPOSE: The diagnosis and treatment of secondary infection of pancreatic necrotic tissue remain a major challenge. The level of soluble triggering receptor expressed on myeloid cells (sTREM-1) in fine needle aspiration (FNA) fluid may be a good marker of infected necrosis.
METHODS: Patients with a clinical suspicion of secondary infection of necrotic tissue were enrolled. The serum levels of C-reactive protein, amylase, procalcitonin (PCT), and sTREM-1 and the fluid levels of sTREM-1, PCT, interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and amylase were examined. When infected necrosis was defined, the first step was percutaneous or endoscopic drainage. If there was no improvement after 72 h, an open necrosectomy was performed.
RESULTS: In 30 patients with suspected infection, 18 patients were diagnosed as having secondary infection of necrotic tissue. The levels of sTREM-1 and PCT in FNA fluid were found to have the closest correlation with the diagnosis of infected necrosis [sTREM-1: area under the receiver operating characteristic curve (AUC) 0.972; 95% confidence interval (95%CI) 0.837-1.000; PCT: AUC 0.903; 95%CI 0.670-0.990, P > 0.05]. A fluid sTREM-1 cutoff value of 285.6 pg/ml had a sensitivity of 94.4% and a specificity of 91.7%. In a multiple logistic regression analysis, an sTREM-1 level of more than 285 pg/ml and a PCT level of more than 2.0 ng/ml in FNA fluid were independent predictors of infected necrosis.
CONCLUSIONS: The fluid level of sTREM-1 will help in the rapid and accurate diagnosis of secondary infection of necrotic tissue in patients with severe acute pancreatitis (SAP).

Lu Z, , et al. Intensive Care Med. 2012 Jan;38(1):69-75. Epub 2011 Oct 27.
human soluble trem-1 elisa assay from aviscera bioscience
human soluble trem-1 elisa kit from aviscera bioscience
Human Soluble TREM1 ELISA Kit
Code No.: SK00218-06
Size: 96T
Price: $420.00 USD
Standard Range:46-3000 pg/mL
Sensitivity:10 pg/mL
Sample Type: serum, EDTA Plasma
Sample volume: 100 uL
Dilution factor: Optimal dilutions should be determined by each laboratory for each application
IntraCV: 4-6%
InterCV: 8-12%
Protocol: PDF
Human Soluble TREM1 ELISA Kit
Code No.: SK00218-09
Size: 96T
Price: $420.00 USD
Standard Range:94-3000 pg/mL
Sensitivity:20 pg/mL
Sample Type: serum, EDTA Plasma
Sample volume: 100 uL
Dilution factor: Optimal dilutions should be determined by each laboratory for each application
IntraCV: 4-6%
InterCV: 8-12%
Protocol: PDF
Mouse Soluble TREM1 ELISA Kit
Code No.: SK00218-03
Size: 96T
Price: $420.00 USD
Standard Range:31-2000 pg/mL
Sensitivity:10 pg/mL
Sample Type: serum, EDTA Plasma
Sample volume: 100 uL
Dilution factor: Optimal dilutions should be determined by each laboratory for each application
IntraCV: 4-6%
InterCV: 8-12%
Protocol: PDF
human soluble TREM-2 elisa kit from aviscera bioscience
Human Soluble TREM2 ELISA Kit
Code No.: SK00218-12
Size: 96T
Price: $420.00 USD
Standard Range:62.5-4000 pg/mL
Sensitivity:20 pg/mL
Sample Type: serum, EDTA Plasma
Sample volume: 100 uL
Dilution factor: Optimal dilutions should be determined by each laboratory for each application
IntraCV: 4-6%
InterCV: 8-12%
Protocol: PDF
 

 

Name
Code No.
Size
Price ($)
Human Soluble TREM1 ELISA Kit (serum, plasma)
96 T
420.00
Human Soluble TREM2 ELISA Kit (serum, plasma)
96 T
420.00
Human Soluble TREM1 ELISA Kit
96 T
420.00
Mouse Soluble TREM1 ELISA Kit
96 T
420.00
Human Soluble TREM2 ELISA Kit
96 T
420.00