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Periostin/Osteonectin (Human) ELISA Kit SK00072-08, Antibody & Proteins
  • PSTN
  • OSF2
Human Periostin ELISA Kit SK00072-08 and Human ECP ELISA Kit SK00128-01 had been used by Dr. Payal K. Naik on follow paper.

Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease without effective therapeutics. Periostin has been reported to be elevated in IPF patients relative to controls, but its sources and mechanisms of action remain unclear. We confirm excess periostin in lungs of IPF patients and show that IPF fibroblasts produce periostin. Blood was obtained from 54 IPF patients (all but 1 with 48 wk of follow-up). We show that periostin levels predict clinical progression at 48 wk (hazard ratio = 1.47, 95% confidence interval = 1.03-2.10, P < 0.05). Monocytes and fibrocytes are sources of periostin in circulation in IPF patients. Previous studies suggest that periostin may regulate the inflammatory phase of bleomycin-induced lung injury, but periostin effects during the fibroproliferative phase of the disease are unknown. Wild-type and periostin-deficient (periostin(-/-)) mice were anesthetized and challenged with bleomycin. Wild-type mice were injected with bleomycin and then treated with OC-20 Ab (which blocks periostin and integrin interactions) or control Ab during the fibroproliferative phase of disease, and fibrosis and survival were assessed. Periostin expression was upregulated quickly after treatment with bleomycin and remained elevated. Periostin(-/-) mice were protected from bleomycin-induced fibrosis. Instillation of OC-20 during the fibroproliferative phase improved survival and limited collagen deposition. Chimeric mouse studies suggest that hematopoietic and structural sources of periostin contribute to lung fibrogenesis. Periostin was upregulated by transforming growth factor-β in lung mesenchymal cells, and periostin promoted extracellular matrix deposition, mesenchymal cell proliferation, and wound closure. Thus periostin plays a vital role in late stages of pulmonary fibrosis and is a potential biomarker for disease progression and a target for therapeutic intervention.
Naik PK et al. Am J Physiol Lung Cell Mol Physiol. 2012 Dec 15;303(12):L1046-56. Full paper
Human Periostin ELISA Kit SK00072-08 had been used on research reports by Dr. Thomson. Thomson NC1, et al. Serum periostin in smokers and never smokers with asthma. Respir Med. 2015 Apr 3. pii: S0954-6111(15)00108-0

Human Periostin ELISA Kit SK00072-08 had been used by Dr. Scichilone N on follow paper: Higher serum levels of periostin and the risk of exacerbations in moderate asthmatics N. Scichilone et al. Asthma Research and Practice 20162:1 DOI: 10.1186/s40733-015-0019-x Received: 16 July 2015Accepted: 19 December 2015Published: 4 January 2016

Human Periostin ELISA Kit SK00072-08 had been used by Dr. Park HY on follow publication. Park HY et al. Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients. Int J Chron Obstruct Pulmon Dis. 2015 Dec 22;11:23-30.

human periostin elisa kit from aviscera bioscience
Human Periostin ELISA KIt
Code No.: SK00072-08
Size: 96 T
Price:
Standard range: 7.8- 500 ng/ml
Sensitivity: 1.9 ng/ml
Sample Type: serum
Sample require: 100 uL per well
Intra-CV:6-8%
Inter-CV: 8-10% 
Protocol: PDF
Ultrasensitive Periostin (Human) ELISA KIt
Code No.: SK00072-05
Size: 96 T
Price: $520.00 USD 
Standard range: 0.18-12 ng/ml
Sensitivity: 100 pg/ml
Sample Type: serum
Sample require: 100 uL per well
Intra-CV:6-8%
Inter-CV: 8-10% 
Protocol: PDF
Periostin (Mouse) ELISA KIt
Code No.: SK00072-03
Size: 96 T
Price: $520.00 USD 
Standard range: 97 - 6000 pg/ml
Sensitivity: 18 pg/ml
Sample Type: serum
Sample require: 100 uL per well
Intra-CV:6-8%
Inter-CV: 8-10% 
Protocol: PDF
human periostin recombinant from aviscera bioscience
Human Periostin/OSf2 Recombinant
Code No.: 00072-01-100
Size: 100 ug
Price: $390.00 USD
Protein ID:Q15063
Gene ID:10631
MW:95 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 95%
Data Sheet: PDF
mouse periostin recombinant from aviscera bioscience
Mouse Periostin Recombinant
Code No.: 00072-03-100
Size: 100 ug
Price: $390.00 USD
Protein ID:Q62009
Gene ID:50706
MW:95 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 95%
Data Sheet: PDF
anti human periostin antibody
Anti Human Periostin IgG
Code No.: A00072-01-100
Size: 100 ug
Price: $260.00 USD
Host: Rabbit
Antigen: human periostin
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC, WB
Working Dilution: IHC 0.5 ug/ml
Data Sheet: PDF
Anti Human Periostin IgG
Code No.: A00072-01-100
Size: 100 ug
Price: $260.00 USD
Host: Rabbit
Antigen: human periostin
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC, WB
Working Dilution: IHC 0.5 ug/ml; WB 2-5 ug/ml
Data Sheet: PDF
anti human periostin antibody
Anti Human Periostin IgG
Code No.: A00072-01-100
Size: 100 ug
Price: $260.00 USD
Host: Rabbit
Antigen: human periostin
Ab Type: Polyclonal IgG
Purification: Protein A
Applications: E, IHC, WB
Working Dilution: IHC 0.5 ug/ml; WB 2-5 ug/ml
Data Sheet: PDF
   

 

Name
Code No.
Size
Price ($)

Periostin/OSF2 (Human) ELISA Kit (for plasma & serum)

96 T

Ultrasensitive Periostin/OSF2 (Human) ELISA Kit (for plasma & serum)

96 T
520.00

Periostin (Mouse) ELISA Kit

96 T
520.00

Periostin (Human) recombinant

00072-01-50
50 ug
220.00

Periostin (Human) recombinant

100 ug
360.00

Periostin (Human) recombinant

00072-01-1000
1 mg
inquire

Periostin (Human) Recombinant (HEK293 cells derived)

10 ug
120.00

Periostin (Mouse) recombinant

00072-03-50
50 ug
320.00

Periostin (Mouse) recombinant

100 ug
490.00

Periostin (Mouse) recombinant

00072-03-1000
1 mg
inquire

Periostin (Mouse) Recombinant (HEK293 cells derived)

10 ug
120.00

Anti Periostin  (Human) IgG

100 ug
260.00

Anti Periostin (Human) Monoclonal Antibody

100 ug
260.00

Anti Periostin (Human) Monoclonal Antibody

A00072-11-100
100 ug
260.00

Anti Periostin (Human) Monoclonal Antibody Clone No.1H9B1 (Capture)

A00072-06-100
100 ug
490.00

Anti Periostin (Human) Monoclonal Antibody

100 ug
260.00

Anti Periostin (Human) Monoclonal Antibody

100 ug
260.00

Anti Periostin (Human) Monoclonal Antibody

100 ug
260.00

Anti Periostin  (Human) IgG, Bionylated

A00072-01-50B
50 ug
360.00

Anti Periostin (Mouse) IgG

100 ug
260.00

Anti Periostin (Mouse) IgG, Biotinylated

A00072-03-50B
50 ug
360.00