Can induce tyrosine phosphorylation of TIE2. Binds to TIE2
receptor and counteracts blood vessel
maturation/stability mediated by angiopoietin-1. Its function may
be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix
contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may
facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal
Moritz Felcht, et al. J Clin Invest. 2012,
doi:10.1172/JCI58832.
Human
Angiopoietin 2 (ANGPT2) ELISA
Code No.: SK00066-06
Size: 96 T
Price:
Standard Range:31.25-4000 pg/ml
Sensitivity:15 pg/ml
Sample Type: cell culture, serum, EDTA plasma
Sample requres: 100uL per well
IntraCV: 4-6%
InterCV: 8-10%
Protocol: PDF
Human
Angiopoietin 2 (ANGPT2) ELISA
Code No.: SK00066-01
Size: 96 T
Price:
Standard Range:93-6000 pg/ml
Sensitivity:30-46 pg/ml
Sample Type: cell culture, serum, EDTA plasma
Sample requres: 100uL per well
IntraCV: 4-6%
InterCV: 8-10%
Protocol: PDF