CTRP7 (Human) ELISA Kit, Recombinant & Antibody |
|
Age-associated loss in adiponectin-activation by caloric
restriction: lack of compensation by enhanced inducibility of
adiponectin paralogs CTRP2 andr CTRP7 |
Hormonal signals from adipose tissue regulate energy
homeostasis but may also be involved in the anti-aging
effects of caloric restriction. The purpose of the current
study was the investigation of age-dependent effects of
caloric restriction on the release of adiponectin, on the
expression and activation of adiponectin-related signaling
and on parameters of altered insulin sensitivity. In young
and in senescent rats, 2 months moderate caloric
restriction reduces serum leptin and insulin (young: -50%;
old: -30%) suggesting increased insulin sensitivity.
However, the same diet enhances serum adiponectin in young
(+60%) but not in senescent (+2%, n=NS) rats. Similarly,
adiponectin expression (visceral fat) and muscular
AdipoR1/2 expression are induced in young rats but not in
senescent rats. The locally produced adiponectin paralogs
CTRP2/7 are elevated in muscular tissues of old animals
(CTRP2 protein: +40%;CTRP7 protein:
+50%) and further induced by caloric restriction but this
does not result in an increased activation of their
downstream target AMPK. Thus, aging is associated with a
partial loss of adiponectin inducibility following
moderate caloric restriction. This loss is not
sufficiently compensated by the locally induced
adiponectin paralogs CTRP2/7, although caloric restriction
results in increased insulin sensitivity in young and in
senescent animals. Thus, the improvement in insulin
sensitivity appears to be independent of adiponectin
induction by caloric restriction in this model.
|
Mol Cell
Endocrinol.2007
Oct 15;277(1-2):26-34. Epub 2007 Jul 19. |
|
 |
 |
|
Code No.: SK00396-09
Size: 96 T
Price: $460.00 USD
Standard range: 1.25 -160 ng/ml
Sensitivity: 200 pg/ml
Sample Type: serum, plasma
Sample require: 100 uL per well
Intra-CV:6-8%
Inter-CV: 8-10%
Protocol: PDF |
|
Code No.: SK00396-08
Size: 96 T
Price: $460.00 USD
Standard range: 0.625 - 40 ng/ml
Sensitivity: 100 pg/ml
Sample Type: serum
Sample require: 100 uL per well
Intra-CV:6-8%
Inter-CV: 8-10%
Protocol: PDF |
|
Code No.: 00396-01-100
Size: 100 ug
Price: $390.00 USD
Protein ID:Q9BXJ2
Gene ID:114905
MW:32.6 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 90%
Data Sheet: PDF |
|
Code No.: 00396-02-100
Size: 100 ug
Price: $390.00 USD
Protein ID:Q9BXJ2
Gene ID:114905
MW:16 KD
Tag: His Tag on N-Terminus
Expressed: E. Coli
Purity: 90%
Data Sheet: PDF |
|
Code No.: A00396-11-100
Size: 100 ug
Price: $290.00 USD
Host: Rabbit
Immunogen: Human CTRP7 Rec.
Antibody Purification: Protein A
Target Protein ID:Q9BXJ2
Target Gene ID:114905
Data Sheet: PDF |
|
|
Name |
Code No. |
Size |
Price ($) |
CTRP7 (Human) ELISA Kit (for plasma & serum) |
|
96 T |
460.00 |
CTRP7 (Human) ELISA Kit (for plasma & serum) |
|
96 T |
460.00 |
CTRP7 Full Length (Human) rec |
|
100 ug |
390.00 |
CTRP7 Globular Form (Human), Rec. |
|
100 ug |
360.00 |
Anti CTRP7 (Human) IgG |
A00396-01-100 |
100 ug |
260.00 |
Anti CTRP7 (Human) IgG |
A00396-02-100 |
100 ug |
260.00 |
Anti CTRP7 (Human) IgG Biotinylated |
A00396-01-50B |
50 ug |
320.00 |
Anti CTRP7 (Human) IgG Biotinylated |
A00396-02-50B |
50 ug |
320.00 |
Anti CTRP7 (Human) IgG |
A00396-11-100 |
100 ug |
290.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1A6B2A5) |
|
100 ug |
310.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1F9A9H6) |
|
100 ug |
290.00 |
Anti CTRP7 (Human) Monoclonal Antibody (2C7F6F4) |
|
100 ug |
310.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1C7D1C11) |
|
100 ug |
310.00 |
Anti CTRP7 (Human) Monoclonal Antibody (2B7C9B7) |
|
100 ug |
310.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1C4F10D9) |
|
100 ug |
290.00 |
Anti CTRP7 (Human) Monoclonal Antibody (2C9H11B6) |
|
100 ug |
310.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1A6B2A5) |
|
50 ug |
350.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1F9A9H6) |
|
50 ug |
350.00 |
Anti CTRP7 (Human) Monoclonal Antibody (2C7F6F4) |
|
50 ug |
350.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1C7D1C11) |
|
50 ug |
350.00 |
Anti CTRP7 (Human) Monoclonal Antibody (2B7C9B7) |
|
50 ug |
350.00 |
Anti CTRP7 (Human) Monoclonal Antibody (1C4F10D9) |
|
50 ug |
350.00 |
Anti CTRP7 (Human) Monoclonal Antibody (2C9H11B6) |
|
50 ug |
350.00 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|